Empyre #6 is the concluding issue of the 2020 Marvel crossover event that brings together the Avengers and Fantastic Four against the alien Cotati invasion. Written by Al Ewing and Dan Slott with art by Valerio Schiti, this installment features a dramatic cover showing key Marvel heroes in the thick of battle. As the finale of this crossover, it marks the resolution of the storyline kicked off in Empyre #1, tying up major plot threads for both the Avengers and Fantastic Four teams. Fans of these characters and the broader Marvel Universe will find this issue an essential part of the Empyre storyline, but there are no widely recognized key events or major first appearances directly associated with this specific issue.
